Larry Squire - Neuroscience of Memory

The role of patients in long-term memory research

Some of the most important distinctions among memory systems in humans have been derived from the careful analysis of behavior of amnestic patients.  The data clearly shows that working memory and long-term memory are two distinct mechanisms that the brain uses to preserve information after a stimulus has come and gone.  Patient data has also allowed to delineate the difference between multiple long-term memory systems - most importantly a declarative memory system which is largely responsible for conscious memory, and a set of skill-based memory systems that are largely unaffected in amnesia.  Controlled animal studies have helped to pinpoint the exact mechanisms underlying these memory systems.

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My path to neuroscience
My path to neuroscience
How I became a neuroscientist
How I became a neuroscientist
The path to neuroscience: A student guide
The path to neuroscience: A student guide
The neurological basis of long-term memory
The neurological basis of long-term memory
What is memory?
What is memory?
Declarative memory in humans and animals
Declarative memory in humans and animals
Non-declarative learning in patients and monkeys
Non-declarative learning in patients and monkeys
The role of patients in long-term memory research
The role of patients in long-term memory research
Additional resources (other sources)
Additional resources (other sources)
Patient E.P. - old KPBS video with Alan Alda
Patient E.P. - old KPBS video with Alan Alda